Biochemical Characterisation of Phage Pseudomurein Endoisopeptidases PeiW and PeiP Using Synthetic Peptides

Pseudomurein endoisopeptidases cause lysis of the cell walls of methanogens by cleaving the isopeptide bond Ala-ε-Lys in the peptide chain of pseudomurein. PeiW and PeiP are two thermostable pseudomurein endoisopeptidases encoded by phage ΨM100 of Methanothermobacter wolfei and phages ΨM1 and ΨM2 of...

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Bibliographic Details
Main Authors: Linley R. Schofield, Amy K. Beattie, Catherine M. Tootill, Debjit Dey, Ron S. Ronimus
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Archaea
Online Access:http://dx.doi.org/10.1155/2015/828693