The YfiBNR signal transduction mechanism reveals novel targets for the evolution of persistent Pseudomonas aeruginosa in cystic fibrosis airways.

The genetic adaptation of pathogens in host tissue plays a key role in the establishment of chronic infections. While whole genome sequencing has opened up the analysis of genetic changes occurring during long-term infections, the identification and characterization of adaptive traits is often obscu...

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Bibliographic Details
Main Authors: Jacob G Malone, Tina Jaeger, Pablo Manfredi, Andreas Dötsch, Andrea Blanka, Raphael Bos, Guy R Cornelis, Susanne Häussler, Urs Jenal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22719254/?tool=EBI