Serum levels of soluble TNF-α receptors but not BDNF are associated with apathy symptoms in mild Alzheimer's disease and amnestic mild cognitive impairment

Serum levels of soluble TNF-α receptors but not BDNF are associated with apathy symptoms in mild Alzheimer's disease and amnestic mild cognitive impairment

ABSTRACT Apathy is intimately associated with dementia. Unfortunately, its pathophysiology remains poorly understood. The motivational impairment that characterizes this disorder might share the same inflammatory mechanisms, as suggested by the sickness behavior theory. Objective: The primary aim o...

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Bibliographic Details
Main Authors: Henrique Cerqueira Guimarães, Paulo Caramelli, Patricia Paes Araujo Fialho, Elisa de Paula França, Marcelo Pelizzaro Dias Afonso, Antonio Lucio Teixeira
Format: Article
Language:English
Published: Associação Neurologia Cognitiva e do Comportamento
Series:Dementia & Neuropsychologia
Subjects:
apathy
dementia
Alzheimer's disease
mild cognitive impairment
TNF-α
sTNFR1
sTNFR2
BDNF.
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642013000300298&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642013000300298&lng=en&tlng=en

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