Comprehensive study in the inhibitory effect of berberine on gene transcription, including TATA box.

Berberine (BBR) is an established natural DNA intercalator with numerous pharmacological functions. However, currently there are neither detailed reports concerning the distribution of this alkaloid in living cells nor reports concerning the relationship between BBR's association with DNA and t...

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Bibliographic Details
Main Authors: Yugang Wang, Michael M Kheir, Yushuang Chai, Jun Hu, Dongming Xing, Fan Lei, Lijun Du
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3161736?pdf=render