Prediction of clinical and biomarker conformed Alzheimer’s disease and mild cognitive impairment from multi-feature brain structural MRI using age-correction from a large independent lifespan sample

Structural neuroimaging has been applied to the identification of individuals with Alzheimer’s disease (AD) and mild cognitive impairment (MCI). However, these methods are greatly impacted by age limiting their utility for detection of preclinical pathology.We built linear models for age based on mu...

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Bibliographic Details
Main Authors: Binyin Li, Miao Zhang, Joost Riphagen, Kathryn Morrison Yochim, Biao Li, Jun Liu, David H. Salat
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:NeuroImage: Clinical
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158220302242