Minocycline attenuates brain injury and iron overload after intracerebral hemorrhage in aged female rats

Brain iron overload is involved in brain injury after intracerebral hemorrhage (ICH). There is evidence that systemic administration of minocycline reduces brain iron level and improves neurological outcome in experimental models of hemorrhagic and ischemic stroke. However, there is evidence in cere...

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Bibliographic Details
Main Authors: Shuhui Dai, Ya Hua, Richard F. Keep, Nemanja Novakovic, Zhou Fei, Guohua Xi
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118301736