The Drosophila amyloid precursor protein homologue mediates neuronal survival and neuroglial interactions.

The amyloid precursor protein (APP) is a structurally and functionally conserved transmembrane protein whose physiological role in adult brain function and health is still unclear. Because mutations in APP cause familial Alzheimer's disease (fAD), most research focuses on this aspect of APP bio...

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Bibliographic Details
Main Authors: Irini A Kessissoglou, Dominique Langui, Amr Hasan, Maral Maral, Suchetana B Dutta, Peter Robin Hiesinger, Bassem A Hassan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000703