The Regulation of ROS- and BECN1-Mediated Autophagy by Human Telomerase Reverse Transcriptase in Glioblastoma

Glioblastoma (GBM) is the most common and aggressive malignant brain tumor with high morbidity and mortality. Human telomerase reverse transcriptase (hTERT), the catalytic subunit of human telomerase, is overexpressed in most cancers including GBM. It is well known that hTERT can compensate telomere...

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Bibliographic Details
Main Authors: Xuelu Ding, Ziyang Nie, Zhaoyuan She, Xue Bai, Qiuhui Yang, Feng Wang, Fei Wang, Xin Geng
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2021/6636510