Changes in the Plasticity of HIV-1 Nef RNA during the Evolution of the North American Epidemic.

Because of a high mutation rate, HIV exists as a viral swarm of many sequence variants evolving under various selective pressures from the human immune system. Although the Nef gene codes for the most immunogenic of HIV accessory proteins, which alone makes it of great interest to HIV research, it a...

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Bibliographic Details
Main Authors: Amirhossein Manzourolajdad, Mileidy Gonzalez, John L Spouge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5042412?pdf=render