Assessment of MMP-2/-9 expression by fluorescence endoscopy for evaluation of anastomotic healing in a murine model of anastomotic leakage.

Disturbance of intestinal wound closure leads to insufficient anastomotic healing and is associated with considerable morbidity following colorectal resections. Matrix metalloproteinases (MMPs) play a crucial role in regulation of wound closure. Here fluorescence endoscopy was evaluated for assessme...

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Bibliographic Details
Main Authors: Philipp-Alexander Neumann, Vanessa Twardy, Felix Becker, Christiane Geyer, Katrin Schwegmann, Annika Mohr, Andreas Faust, Philipp Lenz, Emile Rijcken
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5863981?pdf=render