Acute minocycline treatment prevents neurobehavioral impairment in a rat model of mild blast traumatic brain injury

Acute minocycline treatment prevents neurobehavioral impairment in a rat model of mild blast traumatic brain injury

Mild blast induced traumatic brain injury (mbTBI) and its associated memory impairment and anxiety elevation currently represent one of the major military health challenges. Our earlier work using a rodent model of mbTBI indicated that the pathology underlying the observed neurobehavioral abnormalit...

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Bibliographic Details
Main Authors: Erzsebet eKovesdi, Alaa eKamnaksh, Daniel eWingo, Farid eAhmed, Neil E Grunberg, Joseph B Long, Christine E Kasper, Denes V Agoston
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Neurology
Subjects:
Anxiety
Memory
Neuroprotection
TBI
prevention
anti-inflammatory
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2012.00111/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fneur.2012.00111/full

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