Synthesis and Anti-Bacterial Activities of a Bis-Chalcone Derived from Thiophene and Its Bis-Cyclized Products

A chalcone was prepared by the reaction of terephthalaldehyde with 3-acetyl-2,5-dimethylthiophene. Treatment of this chalcone with thiosemicarbazide/phenyl hydrazine/guanidine hydrochloride/thiourea afforded the corresponding pyrazoline,  pyrazole, and pyrimidine in good yields. All the new compound...

Full description

Bibliographic Details
Main Authors: Abdullah M. Asiri, Salman A. Khan
Format: Article
Language:English
Published: MDPI AG 2011-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/16/1/523/