Combinatory Biomarker Use of Cortical Thickness, MUNIX, and ALSFRS-R at Baseline and in Longitudinal Courses of Individual Patients With Amyotrophic Lateral Sclerosis

Combinatory Biomarker Use of Cortical Thickness, MUNIX, and ALSFRS-R at Baseline and in Longitudinal Courses of Individual Patients With Amyotrophic Lateral Sclerosis

Objective: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative process affecting upper and lower motor neurons as well as non-motor systems. In this study, precentral and postcentral cortical thinning detected by structural magnetic resonance imaging (MRI) were combined with clini...

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Bibliographic Details
Main Authors: Anna M. Wirth, Andrei Khomenko, Dobri Baldaranov, Ines Kobor, Ohnmar Hsam, Thomas Grimm, Siw Johannesen, Tim-Henrik Bruun, Wilhelm Schulte-Mattler, Mark W. Greenlee, Ulrich Bogdahn
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Neurology
Subjects:
amyotrophic lateral sclerosis
magnetic resonance imaging
cortical thickness
MUNIX
ALSFRS-R
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00614/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2018.00614/full

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