Pembrolizumab- and ipilimumab-induced diabetic ketoacidosis and isolated adrenocorticotropic hormone deficiency: a case report

Pembrolizumab- and ipilimumab-induced diabetic ketoacidosis and isolated adrenocorticotropic hormone deficiency: a case report

Abstract Background Several human monoclonal antibodies directed against immune checkpoints, including T lymphocyte antigen 4 and programmed cell death protein 1, have been implemented for cancer treatment in order to promote effector T cell response to tumors. Despite the antitumor activity of thes...

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Bibliographic Details
Main Authors: Thachanun Porntharukchareon, Borwonkhun Tontivuthikul, Nattaya Sintawichai, Panudda Srichomkwun
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Journal of Medical Case Reports
Subjects:
Immune-related adverse event
Diabetic ketoacidosis
Isolated adrenocorticotropic hormone deficiency
Immunotherapy
Immune checkpoint inhibitors
Online Access:http://link.springer.com/article/10.1186/s13256-020-02502-w

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http://link.springer.com/article/10.1186/s13256-020-02502-w

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