Sexually dimorphic metabolic responses mediated by CRF2 receptor during nutritional stress in mice

Abstract Background Chronic stress is a major contributor in the development of metabolic syndrome and associated diseases, such as diabetes. High-fat diet (HFD) and sex are known modifiers of metabolic parameters. Peptide hormones corticotropin-releasing factor (CRF) and urocortins (UCN) mediate st...

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Bibliographic Details
Main Authors: Sreenivasan Paruthiyil, Shin-ichiro Hagiwara, Keshav Kundassery, Aditi Bhargava
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Biology of Sex Differences
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13293-018-0208-4