Yi–Qi–Jian–Pi–Xiao–Yu–Xie–Zhuo Formula Improves Muscle Atrophy via Modulating the IGF-1/PI3K/Akt Signaling Pathway in 5/6 Nephrectomized Rats

Yi–Qi–Jian–Pi–Xiao–Yu–Xie–Zhuo Formula Improves Muscle Atrophy via Modulating the IGF-1/PI3K/Akt Signaling Pathway in 5/6 Nephrectomized Rats

The Yi–Qi–Jian–Pi–Xiao–Yu–Xie–Zhuo (YQJPXYXZ) formula has been used for treating chronic kidney disease (CKD) for many years with good efficiency based on the cumulative empirical experience of previous practitioners. Impairment of the IGF-1/PI3K/Akt signaling pathway plays an important role in medi...

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Bibliographic Details
Main Authors: Hong Xia, Bingbing Zhang, Dan Yang, Chengyue Zhu, Jiudan Zhang, Hongbo Chen, Hongzhen Ma, Shouci Hu, Chao Xu, Chengqian Shi, Keda Lu, Peipei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
Yi-Qi-Jian-Pi-Xiao-Yu-Xie-Zhuo formula
muscle atrophy
insulin-like growth factor l
phosphoinositide 3-kinase
akt
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.624303/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.624303/full

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