Functional polymorphisms in IL13 are protective against high Schistosoma mansoni infection intensity in a Brazilian population.

Functional polymorphisms in IL13 are protective against high Schistosoma mansoni infection intensity in a Brazilian population.

IL-13 is a signature cytokine of the helper T cell type 2 (TH2) pathway which underlies host defense to helminthic infection and activates production of IgE in both parasitized populations and in urban settings after allergen exposure.Two functional polymorphisms in IL13, rs1800925 (or c.1-1111C>...

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Bibliographic Details
Main Authors: Audrey V Grant, Maria Ilma Araujo, Eduardo Vieira Ponte, Ricardo Riccio Oliveira, Peisong Gao, Alvaro A Cruz, Kathleen C Barnes, Terri H Beaty
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3345031?pdf=render

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http://europepmc.org/articles/PMC3345031?pdf=render

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