FXR Mediates Adenylyl Cyclase 8 Expression in Pancreatic β-Cells

Adenylyl cyclase 8 (ADCY8) and Farnesoid X Receptor (FXR) have been identified in pancreatic β-cells and play important roles in insulin secretion. But the mechanisms underlying with respect to the regulation of ADCY8 expression in β-cells, particularly whether FXR is involved, remain unexplored. We...

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Bibliographic Details
Main Authors: Xiangchen Kong, Bingfeng Li, Yushen Deng, Xiaosong Ma
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2019/8915818