Impaired remodeling phase of fracture repair in the absence of matrix metalloproteinase-2

SUMMARY The matrix metalloproteinase (MMP) family of extracellular proteases performs crucial roles in development and repair of the skeleton owing to their ability to remodel the extracellular matrix (ECM) and release bioactive molecules. Most MMP-null skeletal phenotypes that have been previously...

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Bibliographic Details
Main Authors: Shirley Lieu, Erik Hansen, Russell Dedini, Danielle Behonick, Zena Werb, Theodore Miclau, Ralph Marcucio, Céline Colnot
Format: Article
Language:English
Published: The Company of Biologists 2011-03-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/4/2/203