Nucleotide Salvage Deficiencies, DNA Damage and Neurodegeneration
Nucleotide balance is critically important not only in replicating cells but also in quiescent cells. This is especially true in the nervous system, where there is a high demand for adenosine triphosphate (ATP) produced from mitochondria. Mitochondria are particularly prone to oxidative stress-ass...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-04-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/16/5/9431 |