Enhanced oxidative stress response and neuroprotection of combined limb remote ischemic conditioning and atorvastatin after transient ischemic stroke in rats

Enhanced oxidative stress response and neuroprotection of combined limb remote ischemic conditioning and atorvastatin after transient ischemic stroke in rats

BACKGROUND: Limb remote ischemic conditioning (LRIC) and atorvastatin (AtS) both provide neuroprotection in stroke. We evaluated the enhanced neuroprotective effect of combining these two treatments in preventing ischemia/reperfusion (I/R)-induced cerebral injury in a rat model and investigated the...

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Bibliographic Details
Main Authors: Changhong Ren, Sijie Li, Kaiyin Liu, Gary B Rajah, Anbo Zhang, Rongrong Han, Yuanyuan Liu, Qingjian Huang, Haiyan Li, Yuchuan Ding, Xunming Ji
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Brain Circulation
Subjects:
Atorvastatin
ischemia/reperfusion
limb remote ischemic conditioning
nuclear factor erythroid 2-related factor 2 pathway
oxidative stress
Online Access:http://www.braincirculation.org/article.asp?issn=2394-8108;year=2017;volume=3;issue=4;spage=204;epage=212;aulast=Ren

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http://www.braincirculation.org/article.asp?issn=2394-8108;year=2017;volume=3;issue=4;spage=204;epage=212;aulast=Ren

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