STAT3 imparts BRCAness by impairing homologous recombination repair in Epstein-Barr virus-transformed B lymphocytes.
Epstein-Barr virus (EBV) causes lymphomas and epithelial cell cancers. Though generally silent in B lymphocytes, this widely prevalent virus can cause endemic Burkitt lymphoma and post-transplant lymphoproliferative disorders/lymphomas in immunocompromised hosts. By learning how EBV breaches barrier...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-10-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1008849 |
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by Michael T. McIntosh, Siva Koganti, J. Lucas Boatwright, Xiaofan Li, Salvatore V. Spadaro, Alexis C. Brantly, Jasmine B. Ayers, Ramon D. Perez, Eric M. Burton, Sandeepta Burgula, Thomas MacCarthy, Sumita Bhaduri-McIntosh, Nicholas Wallace
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