Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy

Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy

Abstract Background DNA polymerase D (PolD) is the representative member of the D family of DNA polymerases. It is an archaea-specific DNA polymerase required for replication and unrelated to other known DNA polymerases. PolD consists of a heterodimer of two subunits, DP1 and DP2, which contain cata...

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Bibliographic Details
Main Authors: Kouta Mayanagi, Keisuke Oki, Naoyuki Miyazaki, Sonoko Ishino, Takeshi Yamagami, Kosuke Morikawa, Kenji Iwasaki, Daisuke Kohda, Tsuyoshi Shirai, Yoshizumi Ishino
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Biology
Subjects:
Archaea
Replisome
PolD
PCNA
Processive DNA synthesis
Online Access:http://link.springer.com/article/10.1186/s12915-020-00889-y

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http://link.springer.com/article/10.1186/s12915-020-00889-y

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