An Update on Anti-CD137 Antibodies in Immunotherapies for Cancer

An Update on Anti-CD137 Antibodies in Immunotherapies for Cancer

The selective expression of CD137 on cells of the immune system (e.g., T and DC cells) and oncogenic cells in several types of cancer leads this molecule to be an attractive target to discover cancer immunotherapy. Therefore, specific antibodies against CD137 are being studied and developed aiming t...

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Bibliographic Details
Main Authors: Dinh-Toi Chu, Nguyen Duy Bac, Khanh-Hoang Nguyen, Nguyen Le Bao Tien, Vo Van Thanh, Vu Thi Nga, Vo Truong Nhu Ngoc, Duong Thi Anh Dao, Le Ngoc Hoan, Nguyen Phuc Hung, Nguyen Thi Trung Thu, Van-Huy Pham, Le Nguyen Vu, Thuy Anh Vu Pham, Deepak B. Thimiri Govinda Raj
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
CD137/4-1BB
CD137L/4-1BBL
anti-CD137 antibodies
cancer immunotherapies
anti-CD137 antibody therapy
Online Access:https://www.mdpi.com/1422-0067/20/8/1822

Internet

https://www.mdpi.com/1422-0067/20/8/1822

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