Metformin-Associated Lactic Acidosis following Intentional Overdose Successfully Treated with Tris-Hydroxymethyl Aminomethane and Renal Replacement Therapy

A 43-year-old woman was brought to the hospital with severe metabolic acidosis (pH 6.56, bicarbonate 3 mmol/L, and lactate 18.4 mmol/L) and a serum creatinine of 162 μmol/L with a serum potassium of 7.8 mmol/L. A delayed diagnosis of metformin-associated lactic acidosis was made, and she was treated...

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Bibliographic Details
Main Authors: Ngan Lam, Gurbir Sekhon, Andrew A. House
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2012/671595