Angiotensinogen gene silencing reduces markers of inflammation and lipid accumulation in adipocytes

Angiotensinogen gene silencing reduces markers of inflammation and lipid accumulation in adipocytes

Inflammatory adipokines secreted from adipose tissue are major contributors to obesity-associated inflammation and other metabolic dysfunctions. We and others have recently documented the contribution of adipose tissue renin-angiotensin system (RAS) to the pathogenesis of obesity, inflammation and i...

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Bibliographic Details
Main Authors: Wenting eXin, Nishan eKalupahana, Suzanne eBooker, Arnold M Saxton, Nalin eSiriwardhana, Monique eLemieux, Naima eMoustaid-Moussa
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Endocrinology
Subjects:
Adipocytes
Adipokines
Angiotensinogen
Gene Expression Profiling
Gene Silencing
Inflammation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00010/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00010/full

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