The effects of dyslipidaemia and cholesterol modulation on erythrocyte susceptibility to malaria parasite infection

The effects of dyslipidaemia and cholesterol modulation on erythrocyte susceptibility to malaria parasite infection

Abstract Background Malaria disease commences when blood-stage parasites, called merozoites, invade human erythrocytes. Whilst the process of invasion is traditionally seen as being entirely merozoite-driven, emerging data suggests erythrocyte biophysical properties markedly influence invasion. Chol...

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Bibliographic Details
Main Authors: Marion Koch, Jaimini Cegla, Ben Jones, Yuning Lu, Ziad Mallat, Andrew M. Blagborough, Fiona Angrisano, Jake Baum
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Malaria Journal
Subjects:
Plasmodium falciparum
Red blood cell
Host–parasite interactions
Flicker microscopy
Membrane biophysics
Merozoite
Online Access:https://doi.org/10.1186/s12936-019-3016-3

Internet

https://doi.org/10.1186/s12936-019-3016-3

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