Neonatal injury alters adult pain sensitivity by increasing opioid tone in the periaqueductal gray
Studies in both rodents and humans have shown that acute inflammatory pain experienced during the perinatal period produces long-term decreases in pain sensitivity (hypoalgesia) (Grunau et al., 1994a; Grunau et al., 2001; Ren et al., 2004; LaPrairie and Murphy, 2007). To date, the mechanisms underly...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2009-09-01
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| Series: | Frontiers in Behavioral Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/neuro.08.031.2009/full |