Beneficial Action of 2,4,4-Trimethyl-3-(15-hydroxypentadecyl)-2-cyclohexen-1-one, a Novel Long-Chain Fatty Alcohol, on Diabetic Hypoalgesia and Neuropathic Hyperalgesia

The effects of 2,4,4-trimethyl-3-(15-hydroxypentadecyl)-2-cyclohexen-1-one (tCFA15) on diabetic hypoalgesia and neuropathic hyperalgesia were examined. Treatments of streptozotocin (STZ)-pretreated mice with tCFA15 (8 – 40 mg/kg, i.p.) for 7 days significantly reversed the depressed inflammatory noc...

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Bibliographic Details
Main Authors: Yutaka Tamura, Mayuko Monden, Hiroto Suzuki, Masashi Yamada, Keizo Koyama, Hirohito Shiomi
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319344019