Optimizing CAR-T Cell Manufacturing Processes during Pivotal Clinical Trials
Tisagenlecleucel is a CD19-specific chimeric antigen receptor (CAR)-T cell therapy approved for patients aged ≤25 years with relapsed or refractory B cell precursor acute lymphoblastic leukemia (B-ALL) and adults with relapsed or refractory diffuse large B cell lymphoma (DLBCL). The initial tisagenl...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-03-01
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Series: | Molecular Therapy: Methods & Clinical Development |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2329050119301433 |