Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue

During the expansion of adipose tissue adipocyte progenitor cells proliferate and undergo adipogenesis. Here, the authors show that adipocyte progenitor cell proliferation in visceral adipose tissue has a diurnal pattern, which is dependent on both energy intake and the circadian clock.

Bibliographic Details
Main Authors: Aleix Ribas-Latre, Rafael Bravo Santos, Baharan Fekry, Yomna M. Tamim, Samay Shivshankar, Alaa M. T. Mohamed, Corrine Baumgartner, Christopher Kwok, Claudia Gebhardt, Angielyn Rivera, Zhanguo Gao, Kai Sun, John T. Heiker, Brad E. Snyder, Mikhail G. Kolonin, Kristin L. Eckel-Mahan
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23770-0