Maintenance of Genomic Stability in Mouse Embryonic Stem Cells: Relevance in Aging and Disease
Recent studies have shown that mouse embryonic stem cells (mESCs) rely on a distinctive genome caretaking network. In this review, we will discuss how mESCs functionally respond to DNA damage and describe several modifications in mESC DNA damage response, which accommodate dynamic cycling and preser...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-01-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/14/2/2617 |