Should the BCRA1/2-mutations healthy carriers be valid candidates for hematopoietic stem cell donation?

Abstract It’s still not clear whether the mutational status of BRCA-mutated healthy hematopoietic stem cells (HSCs) donors could have an impact on the engraftment. Comparing the studies present in literature, we focused on the correlation between BRCA mutations and the development of hematological m...

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Bibliographic Details
Main Authors: Alberto Fresa, Simona Sica
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Online Access:https://doi.org/10.1186/s13053-021-00179-w