A-to-I RNA Editing in Cancer: From Evaluating the Editing Level to Exploring the Editing Effects

As an important regulatory mechanism at the posttranscriptional level in metazoans, adenosine deaminase acting on RNA (ADAR)-induced A-to-I RNA editing modification of double-stranded RNA has been widely detected and reported. Editing may lead to non-synonymous amino acid mutations, RNA secondary st...

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Bibliographic Details
Main Authors: Heming Wang, Sinuo Chen, Jiayi Wei, Guangqi Song, Yicheng Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.632187/full