A heat-sensitive Osh protein controls PI4P polarity

Abstract Background Phosphoinositide lipids provide spatial landmarks during polarized cell growth and migration. Yet how phosphoinositide gradients are oriented in response to extracellular cues and environmental conditions is not well understood. Here, we elucidate an unexpected mode of phosphatid...

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Bibliographic Details
Main Authors: Deike J. Omnus, Angela Cadou, Ffion B. Thomas, Jakob M. Bader, Nathaniel Soh, Gary H. C. Chung, Andrew N. Vaughan, Christopher J. Stefan
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Biology
Online Access:http://link.springer.com/article/10.1186/s12915-020-0758-x