D-ribose induces cellular protein glycation and impairs mouse spatial cognition.

BACKGROUND: D-ribose, an important reducing monosaccharide, is highly active in the glycation of proteins, and results in the rapid production of advanced glycation end products (AGEs) in vitro. However, whether D-ribose participates in glycation and leads to production of AGEs in vivo still require...

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Bibliographic Details
Main Authors: Chanshuai Han, Yang Lu, Yan Wei, Ying Liu, Rongqiao He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3169629?pdf=render