Notch pathway: a bistable inducer of biological noise?
Abstract Notch signalling pathway is central to development of metazoans. The pathway codes a binary fate switch. Upon activation, downstream signals contribute to resolution of fate dichotomies such as proliferation/differentiation or sub-lineage differentiation outcome. There is, however, an inter...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-10-01
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Series: | Cell Communication and Signaling |
Online Access: | http://link.springer.com/article/10.1186/s12964-019-0453-0 |