Computer-aided assessment of the extra-cellular matrix during pancreatic carcinogenesis: a pilot study

Computer-aided assessment of the extra-cellular matrix during pancreatic carcinogenesis: a pilot study

Abstract Background A hallmark of pancreatic ductal adenocarcinoma is the desmoplastic reaction, but its impact on the tumor behavior remains controversial. Our aim was to introduce a computer -aided method to precisely quantify the amount of pancreatic collagenic extra-cellular matrix, its spatial...

Full description

Bibliographic Details
Main Authors: Fabio Grizzi, Sirio Fiorino, Dorina Qehajaj, Adele Fornelli, Carlo Russo, Dario de Biase, Michele Masetti, Laura Mastrangelo, Matteo Zanello, Raffaele Lombardi, Andrea Domanico, Esterita Accogli, Andrea Tura, Leonardo Mirandola, Maurizio Chiriva-Internati, Robert S. Bresalier, Elio Jovine, Paolo Leandri, Luca Di Tommaso
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Journal of Translational Medicine
Subjects:
Pancreatic adenocarcinoma
Extra-cellular matrix
Degradation
Modeling
Fractals
Online Access:http://link.springer.com/article/10.1186/s12967-019-1817-3

Internet

http://link.springer.com/article/10.1186/s12967-019-1817-3

Similar Items