Claudin-15 overexpression inhibits proliferation and promotes apoptosis of Schwann cells in vitro

Claudin-15 overexpression inhibits proliferation and promotes apoptosis of Schwann cells in vitro

Our previous experiments have discovered that Claudin-15 was up-regulated in Schwann cells of the distal nerve stumps of rat models of sciatic nerve injury. However, how Claudin-15 affects Schwann cell function is still unknown. This study aimed to identify the effects of Claudin-15 on proliferation...

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Bibliographic Details
Main Authors: Jian-Nan Li, Zhan Zhang, Guang-Zhi Wu, Deng-Bing Yao, Shu-Sen Cui
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neural Regeneration Research
Subjects:
apoptosis; Bax; cell proliferation; c-Jun; Claudin-15; nerve regeneration; peripheral nerve injury; protein kinase C alpha; Schwann cells; Wallerian degeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=1;spage=169;epage=177;aulast=Li

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=1;spage=169;epage=177;aulast=Li

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