Shuang-Huang-Lian injection induces an immediate hypersensitivity reaction via C5a but not IgE

Abstract Among traditional Chinese medicine injections, intravenous Shuang-Huang-Lian (IV-SHL) has the highest incidence of injection-induced immediate hypersensitivity reactions (IHRs). The precise mechanisms of IV-SHL-induced IHRs remain ambiguous. In this study, we investigated the mechanisms of...

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Bibliographic Details
Main Authors: Yuan Gao, Rui Hou, Yixin Han, Qiaoling Fei, Runlan Cai, Yun Qi
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-21843-7