Re-Treatment with EGFR-TKIs in NSCLC Patients Who Developed Acquired Resistance

In the era of personalized medicine, epidermal growth factor receptor (EGFR) inhibition with tyrosine kinase inhibitor (TKI) has been a mainstay of treatment for non-small cell lung cancer (NSCLC) patients with an EGFR mutation. Acquired resistance, especially substitution of methionine for threoni...

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Bibliographic Details
Main Authors: Wen-Shuo Wu, Yuh-Min Chen
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:http://www.mdpi.com/2075-4426/4/3/297