Parameter estimation in models of biological oscillators: an automated regularised estimation approach

Parameter estimation in models of biological oscillators: an automated regularised estimation approach

Abstract Background Dynamic modelling is a core element in the systems biology approach to understanding complex biosystems. Here, we consider the problem of parameter estimation in models of biological oscillators described by deterministic nonlinear differential equations. These problems can be ex...

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Bibliographic Details
Main Authors: Jake Alan Pitt, Julio R. Banga
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Bioinformatics
Subjects:
Parameter estimation
Global optimisation
Regularisation
Parameter bounding
Dynamic modelling
Online Access:http://link.springer.com/article/10.1186/s12859-019-2630-y

Internet

http://link.springer.com/article/10.1186/s12859-019-2630-y

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