L-MYC Expression Maintains Self-Renewal and Prolongs Multipotency of Primary Human Neural Stem Cells

L-MYC Expression Maintains Self-Renewal and Prolongs Multipotency of Primary Human Neural Stem Cells

Pre-clinical studies indicate that neural stem cells (NSCs) can limit or reverse CNS damage through direct cell replacement, promotion of regeneration, or delivery of therapeutic agents. Immortalized NSC lines are in growing demand due to the inherent limitations of adult patient-derived NSCs, inclu...

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Bibliographic Details
Main Authors: Zhongqi Li, Diana Oganesyan, Rachael Mooney, Xianfang Rong, Matthew J. Christensen, David Shahmanyan, Patrick M. Perrigue, Joseph Benetatos, Lusine Tsaturyan, Soraya Aramburo, Alexander J. Annala, Yang Lu, Joseph Najbauer, Xiwei Wu, Michael E. Barish, David L. Brody, Karen S. Aboody, Margarita Gutova
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671116301370

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http://www.sciencedirect.com/science/article/pii/S2213671116301370

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