Plasticity in Colorectal Cancer: Why Cancer Cells Differentiate

The cancer stem cell hypothesis poses that the bulk of differentiated cells are non-tumorigenic and only a subset of cells with self-renewal capabilities drive tumor initiation and progression. This means that differentiation could have a tumor-suppressive effect. Accumulating evidence shows, howeve...

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Bibliographic Details
Main Authors: Romina Judith Walter, Steffen Joachim Sonnentag, Véronique Orian-Rousseau, Leonel Munoz-Sagredo
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/4/918