BRCA1 Interacting Protein COBRA1 Facilitates Adaptation to Castrate-Resistant Growth Conditions

BRCA1 Interacting Protein COBRA1 Facilitates Adaptation to Castrate-Resistant Growth Conditions

COBRA1 (co-factor of BRCA1) is one of the four subunits of the negative elongation factor originally identified as a BRCA1-interacting protein. Here, we provide first-time evidence for the oncogenic role of COBRA1 in prostate pathogenesis. COBRA1 is aberrantly expressed in prostate tumors. It positi...

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Bibliographic Details
Main Authors: Huiyoung Yun, Roble Bedolla, Aaron Horning, Rong Li, Huai-Chin Chiang, Tim-H Huang, Robert Reddick, Aria F. Olumi, Rita Ghosh, Addanki P. Kumar
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:International Journal of Molecular Sciences
Subjects:
COBRA1
NELFB
androgen receptor
CRPC
Online Access:http://www.mdpi.com/1422-0067/19/7/2104

Internet

http://www.mdpi.com/1422-0067/19/7/2104

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