Decrease of alpha-chains in beta-thalassemia
In the pathophysiology of beta-thalassemia, globin chain imbalance plays a central role in predicting red blood cell (RBC) life span and disease severity. Strategies to improve globin chain imbalance are therefore a legitimate target in the management of this incurable genetic disorder. Classical ge...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
PAGEPress Publications
2013-03-01
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Series: | Thalassemia Reports |
Online Access: | http://www.pagepressjournals.org/index.php/thal/article/view/1508 |