Decrease of alpha-chains in beta-thalassemia

In the pathophysiology of beta-thalassemia, globin chain imbalance plays a central role in predicting red blood cell (RBC) life span and disease severity. Strategies to improve globin chain imbalance are therefore a legitimate target in the management of this incurable genetic disorder. Classical ge...

Full description

Bibliographic Details
Main Authors: M. Papadaki, George Vassilopoulos
Format: Article
Language:English
Published: PAGEPress Publications 2013-03-01
Series:Thalassemia Reports
Online Access:http://www.pagepressjournals.org/index.php/thal/article/view/1508