Glafenine-induced intestinal injury in zebrafish is ameliorated by μ-opioid signaling via enhancement of Atf6-dependent cellular stress responses

SUMMARY Beside their analgesic properties, opiates exert beneficial effects on the intestinal wound healing response. In this study, we investigated the role of μ-opioid receptor (MOR) signaling on the unfolded protein response (UPR) using a novel zebrafish model of NSAID-induced intestinal injury....

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Bibliographic Details
Main Authors: Jason R. Goldsmith, Jordan L. Cocchiaro, John F. Rawls, Christian Jobin
Format: Article
Language:English
Published: The Company of Biologists 2013-01-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/6/1/146