Diverged alleles of the Anopheles gambiae leucine-rich repeat gene APL1A display distinct protective profiles against Plasmodium falciparum.

Diverged alleles of the Anopheles gambiae leucine-rich repeat gene APL1A display distinct protective profiles against Plasmodium falciparum.

Functional studies have demonstrated a role for the Anopheles gambiae APL1A gene in resistance against the human malaria parasite, Plasmodium falciparum. Here, we exhaustively characterize the structure of the APL1 locus and show that three structurally different APL1A alleles segregate in the Ngous...

Full description

Bibliographic Details
Main Authors: Inge Holm, Catherine Lavazec, Thierry Garnier, Christian Mitri, Michelle M Riehle, Emmanuel Bischoff, Emma Brito-Fravallo, Eizo Takashima, Isabelle Thiery, Agnes Zettor, Stephane Petres, Catherine Bourgouin, Kenneth D Vernick, Karin Eiglmeier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3532451?pdf=render

Internet

http://europepmc.org/articles/PMC3532451?pdf=render

Similar Items