Development and validation of decision rules to guide frequency of monitoring CD4 cell count in HIV-1 infection before starting antiretroviral therapy.

BACKGROUND: Although CD4 cell count monitoring is used to decide when to start antiretroviral therapy in patients with HIV-1 infection, there are no evidence-based recommendations regarding its optimal frequency. It is common practice to monitor every 3 to 6 months, often coupled with viral load mon...

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Bibliographic Details
Main Authors: Thierry Buclin, Amalio Telenti, Rafael Perera, Chantal Csajka, Hansjakob Furrer, Jeffrey K Aronson, Paul P Glasziou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3072996?pdf=render