Establishment and characterization of patient-derived cancer models of malignant peripheral nerve sheath tumors

Establishment and characterization of patient-derived cancer models of malignant peripheral nerve sheath tumors

Abstract Background Malignant peripheral nerve sheath tumors (MPNSTs) are a rare subtype of soft-tissue sarcoma, derived from a peripheral branch or the sheath of the sciatic nerve, brachial plexus, or sacral plexus. The clinical outcomes for MPNST patients with unresectable or metastatic tumors are...

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Bibliographic Details
Main Authors: Rieko Oyama, Fusako Kito, Mami Takahashi, Emi Hattori, Rei Noguchi, Yoko Takai, Marimu Sakumoto, Zhiwei Qiao, Shunichi Toki, Masato Sugawara, Yoshikazu Tanzawa, Eisuke Kobayashi, Fumihiko Nakatani, Shintaro Iwata, Akihiko Yoshida, Akira Kawai, Tadashi Kondo
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Cancer Cell International
Subjects:
Malignant peripheral nerve sheath tumor
Xenograft
Primary culture
Drug screening
Online Access:http://link.springer.com/article/10.1186/s12935-020-1128-z

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http://link.springer.com/article/10.1186/s12935-020-1128-z

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